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Ask Dr. Arun Phophalia Your Own Question
Dr. Arun Phophalia
Dr. Arun Phophalia, Doctor (MD)
Category: Health
Satisfied Customers: 35792
Experience:  MBBS, MS (General Surgery), Fellowship in Sports Medicine
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Please explain meaning: "considering the patient's high mean

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Please explain meaning: "considering the patient's high mean corpuscular volume we need to add B12 and folic acid to her levels". The emergency room Dr said I should talk to my PC physician about treating low levels of B-12 and folic acid. What are the concerns?


Vitamin B12 and/or folic acid deficiency can cause an anemia called as megaloblastic anemia. The deficiency of these causes ineffective red cell formation (ineffective erythropoiesis). This leads to increase in the size of the red blood cells, which is shown by the high mean corpuscular volume. Since the cell size is increased, thus the anemia is called megaloblastic (big cell anemia). A supplement of Vitamin B 12 and folic acid corrects it.

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Dr. Arun

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