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Anthony Bray, MD
Anthony Bray, MD, Doctor
Category: Health
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Experience:  14 years as clinician in the field of Family Practice
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Is the effect of penicillins on bacteria and the enzyme it

This answer was rated:

Is the effect of penicillins on bacteria and the enzyme it blocks a competitive inhibitor or a noncompetitive inhibitor?

Anthony Bray MD :


Anthony Bray MD :

The penicillin's action to block the transpeptidase enzyme in bacteria is as a competitive inhibitor of this enzyme.

Anthony Bray MD :

I hope this helps.

Customer: replied 6 years ago.



If you have further questions then let me know and I will be happy to get back with you.


Best Regards,


Anthony Bray MD

Customer: replied 6 years ago.
Could you tell me where I could find this information to print out or copy

Hello again,


Well I looked it up in an old text of mine >>


Basic and Clinical Pharmacology (forth edition)


I looked up a web article reference that covers the point although it discusses a new drug that is related to the penicillins.


This article may be found at: 567147_2


If you look up this then click Pharmacology and mechanism of Action. About three lines down it states "B lactam antibiotics mimic the substrate for PBP"


Penicillin is a beta lactam antibiotic and PBP stands for penicillin binding protein.


The point is that if the penicillin mimics the substrate then it is competing with that substrate for the site on the enzyme.


I hope this helps. Let me know if you have further questions.


Best Regards,


Anthony Bray MD

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