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Can Lantus Insulin be pre-filled in a syringe to be injected

Resolved Question:

Can Lantus Insulin be pre-filled in a syringe to be injected later? I had heard that pre-filling Lantus syringes was contraindicated.
Submitted: 8 years ago.
Category: Health
Expert:  DR RANDALL replied 8 years ago.


Insulin glargine (Lantus) Should be administered once daily, at any time of day, but should be administered at the same time each day. Cold injections should be avoided. SubQ administration is usually made into the thighs, arms, buttocks, or abdomen, with sites rotated. Cannot be diluted or mixed with any other insulin or solution. Solution should be clear and colorless with no visible particles; inspect solution prior to administration.

These are the forms available in the USA:

Lantus®: 100 units/mL (3 mL) [OptiClik® prefilled cartridge or SoloStar® disposable insulin device]; (10 mL) [vial] one is a prefilled syringe.


Patient information from Lexicomp &


How should I store this medicine?

  • Store unopened containers in a refrigerator. Do not freeze.
  • May store opened vials at room temperature or in refrigerator. If stored at room temperature, throw away any unused portion after 1 month.
  • Store opened cartridges and pens at room temperature. Throw away any unused portion after 1 month.
  • Protect opened containers from heat.
  • Protect opened containers from light.



So the answer is yes using the above precautions or buy the prefilled syringes & don't worry about it.




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