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There are various causes of high WBC. Inflammatory diseases: diseases like bronchitis, asthma, arthritis, or coronary artery disease. Such chronic inflammatory diseases can cause a high WBC. Stress: such as anxiety, overexertion, seizures. Drugs: certain drugs can cause this, such as corticosteroids, lithium, beta agonists. Splenectomy. Leukemoid malignancies: acute leukemias, chronic leukemias, myeloproliferative disordersYou need to discuss with your doctor about these conditions. Sometimes the cause of a high WBC cannot be located. High WBC has also been shown to have a higher than average risk. link.I hope this answer was helpful. If you need more information, feel free to ask. For accepting this answer, please click on the green 'accept' button below. Feedback/Bonus will be warmly appreciated.