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What is monoclonal gammopathy

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what is monoclonal gammopathy
Submitted: 13 years ago.Category: Health
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Answered in 38 minutes by:
9/15/2005
Health Professional: Dr. Gupta, Doctor (MD) replied 13 years ago
Dr. Gupta
Dr. Gupta, Doctor (MD)
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A monoclonal gammopathy indicates the presence of abnormal levels of a protein in the blood. The protein is produced by a group of cells in the bone marrow called plasma cells. Plasma cells are normally found in the bone marrow and represent approximately 1 percent of all marrow cells. They produce the antibodies that help the body fight infection. Abnormal proteins circulating in the blood are not rare. They occur in 1 percent of healthy people over the age of 50 and in 3 percent of people over the age of 70. Monoclonal gammopathy can occur in both sexes and in people of all backgrounds and occupations. In about 80 percent of cases, the abnormal protein does not cause any problems. However, over time, 20 percent of people will experience an increase in the amount of abnormal protein in their blood, which may develop into a more serious condition, including some forms of cancer.
http://www.mayoclinic.org/monoclonal-gammopathy/?WT.mc_id=1&WT.mc_n=OSMX&WT.srch=1
http://www.vetmed.lsu.edu/oncology/monoclon.htm
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Dr. Gupta
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