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Vacuum is used to keep the hubs disengaged. With no vacuum present the hubs should be fully locked to the axle. If you are spinning the wheel with the engine off and there is clicking noise and the axle is not moving, then the teeth on the integrated wheel end (IWE) are not releasing to engage the teeth on the hub. Usually the noise going down the road is caused by a vacuum loss to the IWE's from either a failed IWE vacuum solenoid (least common) or a broken or rubbed through vacuum line between the IWE solenoid and IWE. Most common problems occur around the strut mount bracket and control arm brackets where the line rub through and leak.
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I don't remember saying anything about vibration? Do the axles move on each side when you move each wheel and are they locked solid - if you move either axle it should be solidly locked to each wheel on both sides.
If both axles are locked tight, and fully release with the engine running then I would suspect a failed hub bearing.
Usually the 4x4 not disengaging while driving will result in a ratcheting buzz type noise that will slowdown as you come to a stop. Usually if it is being caused by the hubs not disengaging, shifting to 4x4 will cause the noise to stop. Also a hub not disengaging on one side can noise on the other side.
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