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I did a test prior to purchasing my 08 F350. Two identical super duties engine and transmission and tires all except the 3.73 and 4.10 axle. At 70 mph the 3.73 ran 2050 rpms, the 4.10 ran 2200 rpms. Yes you will notice more power and better take off, however the amount you notice it will be very minimal. To be honest its not worth the expense based on the mods you have done and what appears your wanting to get. You would need a bigger jump like a 4.30 or 4.55 kind of ratio. Do note though, this will decrease your highway fuel mileage.
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