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hi, I really wouldn't use a sealer nor stop leak additive .this will cause you other problems down the line .
to replace the heater core the book calls for around 9 hours labor and it involves removing the dash to get at the heater core ,this is one of those vehicles that they didn't think about for replacing the heater core .
please don't rate me negative because I am giving you bad news
there is no clamps inside the box for the heater core tubes ,just the ones under the hood
there is a video on you tube for a 2003 ranger which is the same ,pretty much for what you have to remove to get the heater core out ..jazzmaster ..
just type in the search box 2006 ford ranger heater core you tube