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What is a safe dose of plaquenil for an 130 pound woman? Is…

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What is a safe dose...
What is a safe dose of plaquenil for an 130 pound woman? Is it a risky drug? I am likely going to be in it for less than a year but afraid to risk my vision. I have had a baseline eye exam which was fine. I do however have some minor prior optic nerve swelling and retinal fiber thinning from a severe infection as a child. More are very minor (only seen on OCT scan) and do not cause vision problems. Is plaquenil an okay medication for me?
Submitted: 3 months ago.Category: Eye
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Answered in 7 minutes by:
1/6/2018
Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago
Dr. Sohaib
Dr. Sohaib, Doctor
Category: Eye
Satisfied Customers: 5,336
Experience: MBBS, FCPS Experienced in all Medical Specialities
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Hello and thank you for the question.
I am Dr. Sohaib, a practicing Consultant with over 13 years of experience and I will do my best to help you today.
Let me review your question for a minute and I will get back to you.

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Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

I would like to ask few details regarding your symptoms/question to assist you more efficiently.

What is the indication?

SLE?

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Customer reply replied 3 months ago
It is going to be pried with another medication for a resistant malaria infection. Likely less than 5mo.
Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

Thank you.

The dose is 200 to 400 mg daily as a single daily dose or in 2 divided doses for rheumatological diseases like lupus.

Due to the risk of retinal toxicity, it is recommended not to exceed a daily dose 400 mg.

For Malaria the dose in chemoprophylaxis is 6.5 mg/kg once weekly (maximum: 400 mg/dose) on same day each week, This is a very low dose as far as retinal side effects are concerned.

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Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

Therefore you need not to worry about retinal side effects, especially given the fact that a baseline exam for eye is normal.

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Customer reply replied 3 months ago
Does my abnormal OCT scan complicate this? Could I have retinal issues in less than 6 mo?
Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

No.

Least likely to have any retinal issues in 6 months. Or even longer given the fact that dose is very low.

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Customer reply replied 3 months ago
Okay thank you. I have heard that damage can continue even after stopping the medication. Should I be corned with this?
Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

In most of the cases, if this happens, it is reversible completely if picked up early.

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Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

So if you experience any visual complaints while you are taking this drug, report this immediately to your doctor. But hopefully this will not happen.

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Eye Doctor: Dr. Sohaib, Doctor replied 3 months ago

Good luck and my sincere wishes for your good health.

Please do not forget to Click and Give 5 Star Rating (at the top of screen) to my service as this is the only way I get credit for my time and expertise on your question.
If you feel you have gotten anything less, please reply back, I am happy to address follow-up questions.
Kindest Regards.

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