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There is nothing that can be done to restore function to her damaged optic nerve...sorry about that.
There are, however, a couple of options to help her with glare from her dilated pupil in her left eye. The safest and easiest would to be fit with a special "cosmetic" contact lens that has an artificial, smaller "pupil" opening. This works well in many situations and I believe it would work for your wife.
Another option involves surgery. In this procedure a suture made of 10-0 proline is passed through her cornea and then her iris. The suture is tied in such a way as to physically pull her iris together forming a, permanent, smaller pupillary opening. This, of course, has all the risks of intraocular surgery however is it is a fairly straight forward procedure that is highly successful in most cases.
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