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SSDI is based on a person's disability, not on their resources. So if the recipient comes into an inheritance, it won't affect their benefits. SS is not affected by resources either.
However, Medicaid is resource based, so it could reduce or terminate any Medicaid benefits until the money was spent down. Medicaid also has a rule that a recipient has to report any changes in their resources within 10 days following the end of the month that someone receives benefits.
According to Medicare,
Under 65 - Generally speaking, if you are under age 65, you will qualify for Medicare if: