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Dr. D. Love
Dr. D. Love, Doctor
Category: Endocrinology
Satisfied Customers: 18462
Experience:  Family Physician for 10 years; Hospital Medical Director for 10 years.
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What does low positive thyroglobulin antibodies are seen in

Customer Question

What does low positive thyroglobulin antibodies are seen in a portion of the asymptomatic populations mean it's <1.0
Submitted: 2 years ago.
Category: Endocrinology
Expert:  Dr. D. Love replied 2 years ago.
Hello from JustAnswer.
Thyroid antibodies are used to assess whether there is any evidence of an autoimmune disorder affecting the thyroid. The can include antibodies to thyroglobulin as well as other antibodies, such as to thyroid peroxidase antibodies and TSH antibodies. However, like other autoimmune antibodies, there are a certain amount of people without thyroid disease that will have a positive test for thyroid antibodies.
In this way, it is similar to the most commonly checked autoimmune antibody test, an ANA test, which will be positive in a certain percentage of normal people.
The likelihood of an autoimmune condition affecting the thyroid is greater when the thyroid antibody tests are more elevated. But the converse is also true - the likelihood of an autoimmune condition affecting the thyroid is less when the thyroid antibody test is only mildly elevated.
So, that is what is meant when someone says that low positive thyroglobulin antibodies are seen in a portion of the asymptomatic population.
In someone with no symptoms and normal function tests, the presence of a mild elevation of thyroid antibodies would only indicate that there is an increased risk of developing overt thyroid disease over years, so ongoing monitoring of thyroid function tests is appropriate.
If I can provide any further information, please let me know.