Sorry, when I read your question and you stated, "It is my business," I thought you were stating to the system that "It's none of your business!" In other words, you didn't want to answer the question, because you considered the issue confidential. Now I realize that you were stating that it actually is your business -- i.e., you're the owner.
With that in mind, there's no effect on your business, beyond the fact that if the U.S. Attorney is instructed by the Trump administration to start enforcing federal marijuana laws again, you could find yourself being prosecuted as an individual for possession of a controlled substance.
As for the effect on your commercial insurance policy, that's something you would have to discuss with the insurance underwriters. As I'm sure you're aware, insurers bend over backwards to avoid actually paying claims. And if there is anything in the policy that states something like, "Illegal conduct is not within the scope of the policy," then your insurer could decline to pay any claim based upon your being proved to be under the influence of a controlled substance.
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