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Ask Dr. Muneeb Ali Your Own Question
Dr. Muneeb Ali
Dr. Muneeb Ali, Doctor
Category: Drug Testing
Satisfied Customers: 7082
Experience:  MBBS, MD, MCCM. Currently working in Critical Care Medicine with 10 year experience in Medicine
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A friend has to take a DOT drug test tomorrow. Yesterday

Customer Question

A friend has to take a DOT drug test tomorrow. Yesterday they took 40 mg of Loperamide, 200mg Cimetidine, and grapefruit juice so that it would pass through the barrier. Will they test positive on a DOT drug test?
JA: Is this a time sensitive issue? What type of specimen are they testing?
Customer: UA DOT test
JA: Anything else in your medical history you think the doctor should know?
Customer: no
Submitted: 4 months ago.
Category: Drug Testing
Expert:  Dr. Muneeb Ali replied 4 months ago.

Hi,
Welcome to JA and thanks for this question. Im sorry to hear about your symptoms. Now i think your friend is very likely to pass a normal DOT drug test, both the drugs which they have used are unlikely to show false positives for any drug. Cimetidine usually does not cause a false positive for any drugs and neither does loperamide. The DOT drug test would NOT pick up on these two drugs and neither will it show them as opiates or any of the other drugs which are being tested for. So your friends test is likely to come back as negative.

EVEN if it comes back as positive (which it wont) he can always go for a GC/MS test to confirm that he did not use any illicit drug and the GC/MS would be able to clear him. But as i said these two drugs should not cause a false positive even though loperamide is a derivative of opioids but it is NOT an opioid itself and thus would not show up on the DOT drug test.

Do you have any more questions?

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