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Hello. My name is***** and I am a veterinarian that can answer your question. I understand Sasha is displaying signs of Cushing's Disease, but the recent test was negative. Some tests are less accurate than others. Do you happen to know the name of the test your veterinarian used (i.e. low dose / high dose dexamethasone suppression, ACTH stim, cortisol/creatinine ratio, etc.)? Also, I am assuming Sasha is drinking more than normal. Can you tell me what other symptoms she has?
Thank you for that information. Cushing's Disease is one of the possibilities for dogs that eat and drink more than normal and with hair loss. The hair loss is most typically around the abdomen. They are also usually panting more and will have what is called a "pendulous abdomen." Other causes of drinking and eating more are diabetes, intestinal disease (i.e. malabsorption), pancreas disease, parasites, Addison's Disease, and neoplasia. A routine blood chemistry will often have an elevated ALP value if Cushing's is suspected. A blood panel will also rule out the majority of other causes except for neoplasia and intestinal related issues. I would recommend to have a fecal exam performed next to rule out parasites, consider a prophylactic dewormer just in case, and look towards having abdominal imaging tests performed (i.e. ultrasound, x-rays). This will hopefully give you a better idea of where the problem is located.
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