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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 29756
Experience:  University of California at Davis graduate veterinarian with 45 years of experience
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PLE symtoms how can this be treated? Chronic explosive

Customer Question

PLE symtoms how can this be treated?
JA: I'll do all I can to help. What seems to be the problem with the dog?
Customer: Chronic explosive diarrea
JA: Where does the dog seem to hurt?
Customer: diagnosed with Ple based on blood work and sym
JA: Can you see anything that looks wrong or different?
Customer: He doesn't seem to have pain and personality is good just seems to be aging fast
JA: What is the dog's name and age?
Customer: Ototaa age 10
JA: Is there anything else important you think the Veterinarian should know about Ototaa?
Customer: Has always seemed overly sensitive to any food changes loose stools etc. Was treated for whipworms and has flukes
Submitted: 4 months ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 4 months ago.

You're speaking to Dr. Michael Salkin. Welcome to JustAnswer. I'm currently typing up my reply. Please be patient. This may take a few minutes.

Expert:  Dr. Michael Salkin replied 4 months ago.

Lymphangiectasia (abnormality of the intestinal lacteal/lymphatics) is the most common cause of a protein-losing enteropathy and the long-term goal is to increase serum albumin concentration. Chronic treatment involves immunosuppressive agents such as corticosteroids (e.g., prednisone) especially when inflammatory bowel disease (IBD) accompanies the PLE. Antibiotic therapy using metronidazole may help control intestinal dysbiosis and provide some antiinflammatory effects. Thromboembolism prophylaxis is warranted with aspirin or clopidogrel. Ultra low-fat diets, hydrolyzed protein or novel antigen diets should be considered in patients with IBD. Elemental enteral feeding products such as Vivones T.E.N. containing free amino acids can be helpful in very compromised patients. Cobalamin, folate, vitamin and mineral supplementation may be necessary in some patients.

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