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Hello, this is Dr. Jess. I am sorry to hear about your dog!!!
I was just looking at an article on Blastomycosis to double check and according to this article, both itraconazole and fluconazole are used to treat blastomycosis, but itraconazole is considered the first choice. I am not sure if your vet chose fluconazole because they are more familiar with its use or if itraconazole is much more expensive (I haven't priced either recently), or for another reason, but I would consult with them and find out if there was a reason behind the decision.