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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 28936
Experience:  University of California at Davis graduate veterinarian with 45 years of experience
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My dog has itp. I would like to know what can be done and

Customer Question

My dog has itp. I would like to know what can be done and will cause death?
Submitted: 10 months ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 10 months ago.

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Expert:  Dr. Michael Salkin replied 10 months ago.

Francesca, acute general treatment of ITP may consist of the following:

prednisone/prednisone - an immunosuppressant

vincristine - an immunosuppressant

mycophenolate mofetil - an immunosuppressant

red blood cell transfusions - given as needed

human IV immunoglobulin - effective in refractory cases

The prognosis is initially guarded, with fatal bleeding into the brain or spinal cord possible. Melena (bleeding from the small intestine) and/or high blood urea nitrogen (BUN) concentration on serum biochemistry profile at initial presentation have been associated with a worse prognosis in some reports. Response to therapy often takes 3-10 days. The survival rate is 84% for dogs diagnosed and treated at a uiniversity referral hospital. Once the platelet count normalizes, the prognosis is fair to good. Many pets may be completely tapered from immunosuppressive medications, although relapse remains possible (9% documented recurrence rate in dogs).

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