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I am sorry to hear what happened with Billy. My name is Rebecca. I am a veterinarian and will do my best to help.
How much does he weigh, so I can calculate how much of a dose he got? We calculate doses and overdoses in mg per kg, so I need to know his weight, but it is unlikely a singe dose of zonisamide will harm him.
If he is a typical 22 to 25 pound Beagle, he got 5 mg per kg, which is not enough to make him sick. He might be a little drowsy,