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Welcome to Justanswer! I am Dr. Altman and happy to assist you both today!Can you please tell me his weight and how long ago this was ingested? Is he a healthy Rottie or have any medical conditions?
The observed effects appear to be associated with toxicity to the central nervous system (CNS) and include convulsions, ataxia (walking drunk), prostration, and death.This is not a medication used in dogs but there are studies for human purposes of toxicityDogs showed above signs, but no deaths, at 60-80 mg/kg/day; a single oral dose of 150 mg/kg was lethal to one animal. Likewise, the minimal lethal dose in the oral single-dose study in mice was 250 mg/kg and several deaths occurred in the 500 mg/kg dose-group.
As a precaution, if your dog ingested this within the last hour then you can induce vomiting with 3% hydrogen peroxide 1 tsp per ten pounds then walk around to mix it in the stomach and agitate the lining. If no vomiting within 10-15 minutes it can be repeated once only in hopes of inducing vomiting.
If it is more than an hour or you are unable to induce vomiting then please monitor closely for the above signs and if seen please seek veterinary attention asapI hope this information makes sense but if it was one 500 mg tablet/ capsule and he is larger than 30 pounds as most Rotties are then you should not see any effects (if healthy) and if they are seen they should be mild and pass readilyPlease let me know how else I can assist you both today
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Here is a European article on studies in dogs. It is very long but does have the above information within for your review:http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/000805/WC500045942.pdfGood luck to you both
Please let me know if I can be of any further assistance to you both today
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Good evening, I wanted to check in with you on your Rottie to ensure there were no issues with the ingestion earlier? I would love an update when you are able
If the information I have provided was helpful I would be grateful if you would rate our chat at the top of the screen so I am compensated for my time. Thank you and best of luck to you both, truly!