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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 29749
Experience:  University of California at Davis graduate veterinarian with 45 years of experience
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Our Saint Bernard 10 month old male just ate 2

Customer Question

***** *****, our Saint Bernard 10 month old male just ate 2 of my wives 2.5mg methotrexate. Not sure what to do?
JA: Thanks. Can you give me any more details about your issue?
Customer: I know that itis a drug also used in dogs
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Submitted: 1 year ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 1 year ago.
Yes, it's usually a part of a protocol for maintenance of canine lymphoma. It's dosed at 2.5 - 5 mg/m squared and so 5 mg for such a large dog represents a very small dose. How much does he weigh, please, so I can be more accurate for you?
Customer: replied 1 year ago.
125 lbs
Expert:  Dr. Michael Salkin replied 1 year ago.
Thank you. 125 lbs = 56.8 kg = 1.5 m squared. 2.5 - 5 mg/m squared x 1.5 m squared = 3.75 - 7.5 mg. I mispoke as 5 mg isn't a very small dose but, instead, a recommended dose for this drug. I would induce emesis by administering 45 mL (3 measuring tablespoons) of 3% hydrogen peroxide by means of a small poultry baster placed between his cheek teeth and cheek. He should vomit within 15 minutes. If not, please repeat the same dose. This is predicated upon his recently (within 90 minutes) ingesting it. Please keep me posted.