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Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 29782
Experience:  University of California at Davis graduate veterinarian with 45 years of experience
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My 2yr old lab/collie/ausie mix has developed open bleeding

Customer Question

my 2yr old lab/collie/ausie mix has developed open bleeding sores on the top of her snout, eyelid, and ankles over the past 3 days. At first she had mild swelling and a bump under the skin on her nose that went away. Next she developed inflamed red bumps on the top of her snout. These seemed to diminish after a dose of 2 regular benadryl, but by the end of the day the sores were oozing clear pus and bleeding. She has an appointment to see a local vet tomorrow morning. Any ideas on the cause? What can I do to treat/comfort her until tomorrow? Is this something that needs to be seen in the ER?
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Submitted: 1 year ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 1 year ago.

I'm sorry to hear of this with your 2 year old. You appear to be describing a cutaneous or mucocutaneous reaction to a topical, oral, or injectable drug. An adverse drug reaction can occur after one treatment, after several treatments or after years of treatment. Cutaneous drug reactions, however, mimic many other skin disorders, especially other immune mediated and autoimmune diseases. If you've seen a positive response to diphenhydramine (Benadryl) you can continue dosing it at 2 mg/lb every 8 hours (not to exceed 50 mg at any one dose). Ideally, treatment with prednisone at 1 mg/lb every 24 hours should be considered. Do you happen to have prednisone (or similar) at home? No, an ER visit isn't necessary.

Customer: replied 1 year ago.
I gave her a dose of topical K9 Advantix II on Feb 11...about a week and a half ago. Could this be the culprit? Otherwise I have not given her any other medication. I can't rule out accidental ingestion of something around the house. I will keep giving her benadryl until tomorrow's vet visit. Thank you for your help!
Expert:  Dr. Michael Salkin replied 1 year ago.

Yes, the Advantix might be incriminated but as I mentioned, if those sores represent a drug reaction it could be something administered to her quite some time ago. Can you upload close-up photo(s) to our conversation? You can use the paperclip icon in the toolbar above your message box (if you can see the icon) or you can use an external app such as

You're quite welcome.

Expert:  Dr. Michael Salkin replied 1 year ago.
I'm just following up on our conversation about your pet. How is everything going?
Dr. Michael Salkin