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We have a 70 lb dog at our shelter that is very depressed…

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We have a 70...

We have a 70 lb dog at our shelter that is very depressed and anxious. We have tried several other anti anxiety drugs that have not been successful and I am wondering if I could as my Vet about cymbalta

Veterinarian's Assistant: Thanks. Can you give me any more details about your issue?

We are an animal shelter. The dog has been her 22 days and has not calmed down. We are a no kill facility but he has not been successful using alprazolam or lorazepam so I was hoping to try something a little different to hopefully give him some relief from the fear issues he is exhibiting.

Submitted: 2 years ago.Category: Dog Veterinary
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Answered in 24 minutes by:
1/25/2016
Dog Veterinarian: Dr. Michael Salkin, Veterinarian replied 2 years ago
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 34,269
Experience: University of California at Davis graduate veterinarian with 45 years of experience
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While Cymbalta (duloxetine) is reasonably safe (no deaths were seen in dogs at the high dose of 45mg/lb daily) it's also unpredictable in its effects. We usually see sedation at 0.5 mg/lb but tremors at 5 mg/lb and as the dose increases, agitation, aggression, panting, sedation, tachycardia (increased heart rate), drooling, vomiting, diarrhea, tremors, and seizures may arise. I would consider an SSRI such as fluoxetine or paroxetine in combination with reconditioning under the guidance of a veterinary behaviorist. Does your shelter have such a behaviorist on retainer as do many ASPCA shelters?

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