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No, tetrasodium EDTA should not cause any urinary changes. Instead, I am suspicious of a urinary tract infection or urinary stones.
I recommend having her evaluated as soon as you can. I would start with a physical exam, a urine sample for analysis as well as a bacterial culture, and then start her on antibiotics. We may also consider x-rays to look for urinary stones, but this is not entirely necessary (if this is her first urinary problem) unless the vet palpates something abnormal during her exam. If she has a history of repeated urinary issues, I would pursue x-ray now as well.