Welcome to Justanswer! I am Dr. Altman and happy to assist you both today!
With your dog's size being 100 pounds (45 kg) that would make this ingestion of 0.050 mg a concentration to him at 0.001 mg/kg ingestion.
This toxin can cause:
Level of toxicity: Generally moderate to severe, depending on the amount ingested, time of ingestion, active ingredient, and concentration of the product
Common signs to watch for:
Bromethalin poisoning is not treated with Vitamin K1! Bromethalin works by uncoupling oxidative phosphorylation in the brain and liver mitochondria and can result in brain swelling (cerebral edema).
In toxicity trials, the oral toxic dose of bromethalin when used as part of bait appears to be much lower than the dose administered as a technical grade agent. For example, in dogs, an average lethal dose of technical grade bromethalin is reported to be 4.7 mg/kg but 2.38 mg/kg in bait. Young dogs (<1 yr old) appear more sensitive; death has been reported at dosages of ~1 mg/kg in bait. Dogs are more commonly involved.
Even though this ingestion is way below the toxic dose if the ingestion was within the last hour then you can induce vomiting with 3% hydrogen peroxide 1 tsp per ten pounds (i.e. 3 tbsp for his size) then walk around to mix it in the stomach and agitate the lining. If no vomiting within 10-15 minutes it can be repeated once only in hopes of inducing vomiting.
It simply is not worth the risk with this product. One site lists:
At a bromethalin dosage of 0.1–0.49 mg/kg in dogs (more than what was ingested in this scenario), or 0.05-0.1 mg/kg in cats, emesis alone within 4 hr of exposure may be adequate. If emesis is not successful, or if > 4 hr have elapsed since ingestion, a single dose of activated charcoal at 1–2 g/kg body wt is indicated. Whenever administering activated charcoal, the clinician must remain aware of the risk of aspiration or hypernatremia secondary to fluid shift into the gut. The clinical signs of acute hypernatremia may mimic those seen with bromethalin toxicosis.
I hope this information makes sense but please let me know if I can be of any further assistance tonight. Activated charcoal would be a treatment through your veterinarian or a veterinary er if warranted
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