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Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 28503
Experience:  University of California at Davis graduate veterinarian with 45 years of experience
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How is clavamox still effective after expiration date?

Customer Question

How long is clavamox still effective after expiration date?
Submitted: 1 year ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 1 year ago.

Percentage concentrations of reconstituted amoxicillin-clavulanate potassium powder (Clavamox, e.g.) were over 90% up to the fifth day, degradation was extensive by the seventh day with amoxicillin concentration falling below 80% while clavulanate had values less than 70% at seven days post-reconstitution. The foil wrapped tablets are likely to remain stabile, however, up to 6 months (at least; one study showed stability up to 48+ months) past-expiration with any degradation likely to be insignificant as to clinical effectiveness. It does not remain stabile outside the foil wrapping and so only one tablet should be unwrapped at a time. Please respond with further questions or concerns if you wish.