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Rebecca, Dog Veterinarian
Category: Dog Veterinary
Satisfied Customers: 15154
Experience:  More than 30 years of companion animal practice.
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I am a family doctor MD, but our 13 yr old lab with slow

Customer Question

I am a family doctor MD, but our 13 yr old lab with slow growinglymphoma has started acting wild-eyed and restless, she has had prescribed by our vet, 20mg twice daily of prednisone, 25-50 mg promethazine/ phenergan at night + tramadol20-30 mg TID for neck/ joint pains. She looks mildly confused, moderately ataxic, and very hungry.
Submitted: 1 year ago.
Category: Dog Veterinary
Expert:  Rebecca replied 1 year ago.


I am sorry to hear you are concerned about your Labrador. My name is***** am a veterinarian with 30 years experience. How long has she been taking these medications? Tramadol or prednisone could affect her this way.

Customer: replied 1 year ago.
Tramadol x 2 months, prednisone x 2 weeks, promethazine x 1 week
Expert:  Rebecca replied 1 year ago.

Promethazine can have sedative qualities especially if given with a drug like tramadol that can also act as a sedative. Is it being given for vomiting? How much does she weigh? The dose for an average Labrador weighing 65 pounds would be 6 to 15 mg.

Expert:  Rebecca replied 1 year ago.

where is the slow growing lymphoma located, is it GI, peripheral nodes?

Customer: replied 1 year ago.
25mg promethazine, lymphoma most prominent in the neck but is eating very well on prednisone, does have slight every 1-3 minute single retching type of dry cough if lays on the neck. Trying to decide if med side-effects are making her confused/ weak or time to put her down.
Expert:  Rebecca replied 1 year ago.

Have you consulted with an oncologist, or considered chemotherapy? It does sound like the confusion could be from the tramadol and/or the promethazine. If the promethazine is for nausea and vomiting, you might try maropitant, or even famotidine.

Expert:  Rebecca replied 1 year ago.

I would consider putting her down if she is not eating well. If she still has an appetite, she may yet have some good days to come.

Customer: replied 1 year ago.
Thanks, ***** ***** to do chemo, just going for comfort. TCH
Expert:  Rebecca replied 1 year ago.

Then I would stop the promethazine, and try famotidine. If she is 65 pounds, I would give 10 to 20 mg up to twice daily. If that does not help, I would ask your veterinarian for the maropitant.

Let me know how she is doing and what other questions you have. Kindly consider rating my answer; you can still get back to me with questions and updates after rating.

Expert:  Rebecca replied 1 year ago.

Did you leave the conversation? Can I help with anything else?

Expert:  Rebecca replied 1 year ago.

Professional to professional, may I ask why you're not getting back to me? Can I help with or answer anything else?