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Good Morning and welcome! I am Dr. Loretta, a licensed veterinarian and I am happy to answer your question.
This lethargy could come from anything...Infection, digestive disturbance, injury that you may not be aware of. For now, if there is no vomiting, try giving your guy aspirin at 5 mg per pound every 12 hrs ONLY if he is eating. This will bring down a fever if this is an infection and will help with pain if there is an injury. It is hard to know if your guy should go to the ER clinic with this little information. If you can fill em in on his age and history, that will be very helpful.Does that make sense to you?
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Thanks for that information...I would think, from your description, that Buddy may have injured a disc in his back causing pain or has aggravated an already present arthritis causing pain. These can both happen only by moving the wrong way or jumping up or down on something. Try the aspirin at 5 mg per pound every 12 hrs given with food to see if you can see any improvement before rushing to the ER vet.