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Hi. Welcome to Just Answer. My name is***** and I've been a veterinarian for 15 years. How long has this "blister" been there? Is he holding the eye shut / acting like it is painful? Can you take a picture and post it for me to view it?
Thank you for getting back to me. I'm going to be very honest here and say that this situation has me very concerned. If there is something on the actual eye (the clear part) that is looking like a blister that is painful (holding the eye shut), then there is a large concern for an ulcer there. Anytime I have an eye situation where the pet is holding the eye shut / squinting, that shows it is uncomfortable / painful. I don't take eye situations lightly as they can in some situations progress to visually threatening situations. IF this is an ulcer, it could progress to a deeper one that eventually could rupture and possibly compromise the eye. I would strongly recommend getting to a vet's office as soon as possible for them to first hand evaluate what is going on and then start up therapy for it. I'm hopping for the best.
If it is an actual ulcer on the corneal (a corneal ulcer), then it would absolutely be an after hours emergency situation. I again just don't like to take eye situations for granted that they aren't emergencies as at my ER, I've seen numerous very critical eye situations that weren't dealt with soon enough by owners and they got a lot more progressed.