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I have a English Mastiff aged 11years 3 months She has had…

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I have a English Mastiff...
I have a English Mastiff aged 11years 3 months She has had excellent general health. For the past 2 years is on Carprofen 150mg per day. for arthritis. This past year she has excessive urination and was prescribed Propalin which worked for awhile. She then became incontinent and the vet prescribed sudafed 60mg per day this works 50% of the time. Ithink she would go through a bucket of water a day and would urinate the same amount. I take her outside every hour or so as she may be forgetful. Sometimes she can't make it out side and I have huge puddles across the floors. I had a full blood profile 6 months ago and everything was excellent. A urine sample showed very clear urine and was prescribed a course of antibotics. Can you help I'm desperate I will not put her down she is not in any pain appetites good, just this problem of incontenence.

Regards Elizabeth
Submitted: 8 years ago.Category: Dog Veterinary
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Answered in 4 minutes by:
6/29/2010
Dog Veterinarian: Dr. Gary, Dog Veterinarian replied 8 years ago
Dr. Gary
Dr. Gary, Dog Veterinarian
Category: Dog Veterinary
Satisfied Customers: 20,006
Experience: DVM, Emergency Veterinarian, BS (Physiology)
Verified
Hello Elizabeth,

I would first recheck the bloodwork and make sure our kidneys and liver are functioning normally. We recommend bloodwork every 6-12 months when on chronic NSAIDS like Rimadyl (Carprofen) and more frequent in dogs this old.

If the bloodwork is normal, then I'd try Proin (Phenylpropanolamine) to help strengthen the urethral sphincter. If that does not help, then I would try Estradiol therapy. This does have it's complications- bone marrow suppression- but it's the only other medication to help with incontinence that may be of some benefit here.

I hope this helps, let me know if you have any other questions.
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