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Mark Bornfeld, DDS
Mark Bornfeld, DDS, Dentist
Category: Dental
Satisfied Customers: 6015
Experience:  Clinical instructor, NYU College of Dentistry; 37 years private practice experience in general dentistry, member Academy of General Dentistry, ADA
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Is there an antidote to local anesthesia

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Is there an antidote to local anesthesia???
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Different local anesthetic products have different durations of action. For example, marcaine has a very long action, whereas lidocaine without a vasopressor ingredient has a very brief duration of action. So, to a certain extent, the duration of numbness can be modulated by selection of an anesthetic with a duration of action appropriate to the length of the procedure.

An alternative suggested by your question is a medication that reverses local anesthetic-- phentolamine mesylate, marketed under the name OraVerse (see This drug allows the use of more potent anesthetics for the procedures that warrant them, and still permits termination of anesthesia at an appropriate time.

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