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When was the last time Archie had full blood work done to check liver and kidneys and pancreas?
Has he had any imaging to try and pinpoint the cause of his weight loss?
You may consider getting an ultrasound done to check the pancreas and make sure there are no small tumors (not palpable during physical exam) that could explain why he went back to being insulin dependent. It could also give you answers as to why he is losing weight. For instance, he may have a mild form of inflammatory bowel disease in which his only symptom is weight loss.
You can also try adding in a feline probiotic into his food to help his body process and absorb nutrients better and give it a few weeks to see if he gains the weight back.
A good one available on amazon.com is called Feline Fortiflora
An ultrasound will also evaluate his other organs and make sure there are no abnormalities which could account for his weight loss. You can also consider checking his vitamin B levels which can become lowered in an older cat and cause weightloss.
Good luck with Archie
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This Content is not intended to be a substitute for a professional veterinary exam, diagnostics, diagnosis, or treatment. Always seek the advice of your attending veterinarian with any questions you may have regarding a medical condition of a pet.
Yes arthritis hurts but the metacam will manage that. Vitamin B injections are better than oral.
Good luck let me know how it goes
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