How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Anna Your Own Question
Anna, Pet Expert/Biologist
Category: Cat Veterinary
Satisfied Customers: 11424
Experience:  40 yrs.: herps, pocket pets, rabbits, poultry, dogs, horses. Biology degree. Vet assistant.
Type Your Cat Veterinary Question Here...
Anna is online now
A new question is answered every 9 seconds

I have a cat with oral cancer. I want to give him Berberine,

Customer Question

I have a cat with oral cancer. I want to give him Berberine, but don't know the dosage I should use. He is 10 pounds, what is the right dosage for his weight?
JA: I'm sorry to hear that. What is the cat's name?
Customer: Spike
JA: Is there anything else the Veterinarian should be aware of about Spike?
Customer: He is on an antibiotic for an infection related to his oral cancer
Submitted: 6 months ago.
Category: Cat Veterinary
Expert:  Anna replied 6 months ago.


I apologize that no one has responded to your question sooner. Different experts come online at various times. I just logged on and saw your question. My name is ***** ***** I’m a biologist with a special interest in alternative medicine for pets. I'm sorry to hear of Spike's diagnosis.

The reason you can't find a dosage of Berberine for cats is that no dosages have been established. Some studies have been done on cats to determine possible side effects. The lowest dose used was 5 mg per kg of body weight. A kilogram is about 2 pounds. At that dose, the cats suffered temporary neurological symptoms that resolved on their own. That included loss of control of bladder and bowels, and retching.

The Berberine was injected because it tastes so awful most cats won't eat it, even when mixed with something tasty. You can read the whole study here:

I suspect you got your information about Berberine from human alternative medicine sites. There is some evidence that it can reduce breast tumors in women. However, in a study with rats, it was found to cause liver tumors. It's most common use if for diabetes and it does help with that. If you decide to use it with Spike, I would go with the lowest amount from the cat study, which is the amount I gave you above. You can crush a tablet and mix it with water. Then you'll have to use a syringe to put it in his mouth. You'll most likely have to hold his mouth shut and wait fro him to swallow. Some cats will take it if it's mixed with tuna, but that doesn't work for most.

One of the most promising holistic cancer therapies is the use of medicinal mushrooms. Certain species of mushrooms have been found to suppress the growth of cancer cells and boost the immune system. Here is a source of a mushroom supplement made just for pets:
I highly recommend that you take a look at the following link. It is a directory of available information for owners of cats with cancer. There are dozens of links given for supplements alone, and the information comes from reliable sources. I couldn't begin to give you a fraction of what you'll find there:

If you have more questions, just let me know. I hope that whatever you do, it will work out well for Spike.


My goal is to provide you with excellent 5 star service – if you feel you have gotten anything less, please reply back, I am happy to address follow-up questions. Please remember to rate my service after you have all the information you need. I will greatly appreciate a positive rating as that is the only way I am compensated. Thank you!

Expert:  Anna replied 6 months ago.

Hello again. Do you need any additional information?