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Hello, this is Dr. Jess. I am sorry to hear about your cat! Can you tell me how long the decreased appetite and weight loss has been going on? Is she having any vomiting or diarrhea?
Is she drinking water normally? or more or less water than usual?
Is she urinating normally?
Any accidents outside the litterbox?
Ok. An episode like this going on for two weeks is concerning that something serious is going on, particularly if she is losing weight rapidly. There are a number of possible causes. We could have something like a partial foreign body obstruction from the mouse. We also worry in an older cat with weight loss and decreased appetite about liver or kidney disease causing nausea and inappetance, we worry about diabetes (though we often see increased thirst and urination with this) as well, or issues with the gall bladder or pancreas.
I would highly recommend making an appointment with your vet ASAP for an exam, some bloodwork and an x-ray to evaluate her and look for an underlying cause of these symptoms. We do worry very much about cats who go too long without eating, as they can develop a problem called hepatic lipidosis (particularly in cats who may have been overweight starting out).
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