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Hi this is Dr. Hill. I am sorry Shake is having problems. Give me a moment to read your question.
So entoderm is meant to be used short term for minor areas of inflammation and superficial infection. If the lesion on his chin has now spread down his neck then you need to stop the Entederm. He needs to have the area clipped and cleaned with an antibacterial solution and will likely need antibiotics. Sometimes a superficial dermatitis can get worse when kept moist. Clipping it and cleaning it will allow it to dry out. As far as his appetite is concerned, it could be a combination of licking the entoderm and not feeling well from the sore. He really should be taken in to your local veterinarian to have it rechecked.