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This is Dr. KV. I'm here to help with Lulu. It sounds like her anal glands may be impacted and need to be drained. It is best to wait to allow your vet to do this when they open later this morning. Until then, you can try to gently warm compress her hind quarters with a warm dish towel. This will help with some discomfort.
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Good luck with Lulu today.
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