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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Cat Veterinary
Satisfied Customers: 29058
Experience:  University of California at Davis graduate veterinarian with 45 years of experience.
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What brand of nattokinase can I give to my sweet ragdoll cat

Customer Question

Hi. What brand of nattokinase can I give to my sweet ragdoll cat who today suddenly had an arterial thromboembolism and started dragging her limp hind quarters while walking. I'm in shock, but from knowing alot about natural remedies I'm inclined to think nattokinase is probably the only thing that will help her. It sure helped my husband. He's taken Dr's Best over a yr. with great benefit. I'd sure like a speedy reply because we're out of it and I'll be order it from Amazon tonight. Thanks. Hanna
Submitted: 1 year ago.
Category: Cat Veterinary
Expert:  Dr. Michael Salkin replied 1 year ago.

I'm sorry that your question wasn't answered in a timely manner. Please know that treatment of arterial thromboembolism (ATE) is entirely anecdotal and without substantial clinical trials to demonstrate benefit or harm. Most studies of acute therapy consist of small case series. Treatment of acute ATE can be divided into several aims: thrombolysis, promotion of collateral circulation, prevention of additional thrombosis, control of pain, and treatment of any underlying heart disease. Thrombolytic therapy has been attempted with various chemical and mechanical approaches, including nattokinase, streptokinase, urokinase, tissue plasminogen activator, and most recently, intravascular thrombectomy. All of these approaches resulted in either substantial periinterventional mortality (e.g. reperfusion injury) or failed to resolve the thrombus. Thus, this expert can't recommend aggressive thrombolytic therapy in acute ATE.

If you were to try any medical approach, clopidogrel bisulfate (Plavix) - a once-daily platelet aggregation inhibitor - may be useful in preventing thromboembolic disease in cats. It may improve pelvic limb circulation in cats after a cardiogenic embolic event. Once again, there's little scientific evidence and no general consensus as to this drug's value in cats such as Miyu. In one trial it did result in longer survival times after an initial thromboembolic event when compared to aspirin. Please respond with further questions or concerns if you wish.

Expert:  Dr. Michael Salkin replied 1 year ago.
I'm just following up on our conversation about your pet. How is everything going?
Dr. Michael Salkin