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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Cat Veterinary
Satisfied Customers: 29793
Experience:  University of California at Davis graduate veterinarian with 45 years of experience.
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My 14 year old is in kidney failure, I'm quite sure. I have

Customer Question

My 14 year old is in kidney failure, I'm quite sure. I have been pushing pedialyte via syringe, 6 ml at a time. I plan on euthanasia this week but in the mean time, I am trying to keep him comfortable. How much of an 8mg Zofran tab can I give him? He probably weighs approximately 5 lbs
Submitted: 2 years ago.
Category: Cat Veterinary
Expert:  Dr. Michael Salkin replied 2 years ago.
Aloha! You're speaking with Dr. Michael Salkin
Zofran is an antiemetic dosed within a wide range - 0.05-0.5 mg/lb every 6-12 hours. A recent study suggests that the dose should be nearer the higher end of that range. An over the counter antacid such as famotidine (Pepcid) dosed at 0.25 mg/lb once daily should afford Socks comfort as well. I'm not familiar with Verena, however. What is the generic name for the drug in Verena, please?
Customer: replied 2 years ago.

Sorry I misspelled the name. It is Cerenia 60mg tab

Expert:  Dr. Michael Salkin replied 2 years ago.
Ah! Cerenia (maropitant) - another antiemetic - is dosed at 0.5 mg/lb daily for up to 5 consecutive days. I think it'll be too difficult to dose down a 60 mg tab, however.
Please continue our conversation if you wish.
Customer: replied 2 years ago.

I tried giving him the pepcid and he started foaming at the mouth and vomited. How about a promethazine suppository 25mg?

Expert:  Dr. Michael Salkin replied 2 years ago.

There's relatively little experience with promethazine in cats; it's not frequently recommended for use. In one study, 1 mg/lb intramuscularly given 1 hour prior to xylazine (which acts as an emetic in cats) significantly reduced the frequency of emesis (Kolahian, et al., 2012). 25 mg would be excessive - by any route. A mild overdose would be likely to sedate and cause dry mouth; a significant overdose might cause torticollis, tremor, and salivation.

Expert:  Dr. Michael Salkin replied 2 years ago.
Hi Veronika,

I'm just following up on our conversation about your pet. How is everything going?

Dr. Michael Salkin