Cardiology Questions Answered by Verified Cardiologists.
Hello. This is Dr. Alan. One of the components of Ziak is bisoprolol. This is a class of drugs are known as Beta blockers. These drugs can cause fatigue, loss of energy and depression; among other things. It can also cause loss of libido and sexual dysfunction in men. Many of the symptoms you describe are typical for depression. The fact that you felt better after stopping it would suggest that you might be having drug related side effects. That being the case you should ask your doctor to put you on a different class of blood pressure medicine. There are many other non-beta blocking drugs to choose from.
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Beta blockers block beta receptor sites in various parts of the body that react to normally produced neurotransmitters such as epinephrine and nor-epinephrine These neurotransmitters act to increase pulse, constrict arteries and make the heart beat more forcefully. This can raise the blood pressure. Beta receptors are present in many organs, including the heart which has Beta 1 receptors. Blocking effects can be to slow the pulse, relax heart contraction and dilate small arterioles; thus reducing blood pressure. Bisoprolol is supposed to be"selective" for Beta 1 receptors; however many people simply do not tolerate them because they still may cross the blood-brain barrier and have effects on the central nervous system. There is absolutely nothing wrong with them per se because they are one of the most commonly used drugs for BP control and other reasons, such as in coronary patients to take stress off the heart. Tell your doctor what has happened to you and that you felt better when you were not taking it. A doctor can never predict ahead of time if something will not be tolerated well. All drugs have potential side effects; so it is often the case that you will have to work with your doctor on a trial and error basis , until you find something that works and does not produce side effects.
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I explained beta blocker selectivity to you; and also the fact that despite this some people do not tolerate them. I suggested that you might be depressed, but also felt that it might be the drug because you said you felt alive again after you stopped it. I can only make suggestions and it is not my role to get between you and your doctor's care. He knows your overall condition better than I do. If he does not want to give you a trial off the Ziak; and thinks you need treatment for depression, unfortunately I cannot do anything about that.
My opinion stands. You will not know if the Ziak is giving you side effects unless you stop taking it; under medical supervision. If you don't feel better, then it is not the drug. If you feel as though your doctor is not listening; then you should solicit another opinion. The diagnosis and treatment of depression should be done under careful direct supervision and follow up. I sense your frustration. and I am only trying to indirectly help the best way I can.
Yes. Get a new doctor, who is willing to take you off your Ziak first. If that doesn't make you feel better then he/she can help you can go from there; possibly with a complete new evaluation. You are correct about drugs like Cilift. Suicidal ideation can occur in the beginning of treatment; and patients who start these drugs need careful monitoring. They also can have numerous other side effects. You are also correct that it is not a new medication. You are not at a dead end. You just need to start over.