It sounds like the Brake is locked, bad wheel bearing or frozen axle.
You will need to remove the Brake Drum or Brake Caliper (if disc brakes) to inspect
After removing the Rim & Tire, the Brake should look like one of these:
After removing Rim & Tire, you will need to see if the Drum will turn by hand.Be sure the vehicle is safely raised & blocked.Transmission in neutral & brake Off.If you cannot turn the Drum, then you will have to try to back the Brake Lining off inside by:
Remove one wheel bolt, then push adjusting wedge upwards with a suitable screwdriver through wheel bolt hole to back off brake shoes.
A Brake tool looks like a Bent Flat Blade Screw Driver on both sides, without a handle.
You insert one end thru the adjusting hole in the back & turn the Brake Adjuster to loosen or tighten the Brake Shoes
You can try a large Flatblade, but usually it won't work because of the angle.Most Parts stores sell them for a couple of dollars.
You might also try taping on drum with a hammer, to get as much Brake Dust out & see if the Brakes will loosen to remove drum.
As Posted earlier:
You will need to turn the adjusting wheel inside with a brake tool to back off the Brake Pads, to remove the Drum.Once the Drum is off, see if the Axle will turn freely.If so, then it was your Brakes If not, then check the Axle Bearing