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Hello my name is***** but you can call me Dr. H, and I am a licensed veterinarian. I understand your pet is currently being treated with Prednisone for a rash, but is currently having some panting, shaking and decreased appetite with a hardened stomach.
Panting is an adverse effect that can be seen with steroid use. The decreased appetite however isn't seen nor is the hardened stomach. I suspect there may be another cause for these symptoms. Has he eaten anything besides his normal kibble recently? What is his normal diet?
- Dr. H
Ok. That is a good call
Then yes vomiting and panting are signs of a potential adverse reaction to the Prednisone. Increased urination, drinking and eating are commonly seen and considered normal. It is only safe to stop this medication abruptly if given for 7 days or less to avoid potential iatrogenic effects on the adrenal glands. So you will have to slowly wean him off the medication over the course of 4 days, by giving it every other day.
To help with the adverse symptoms you can give him a bland diet of boiled plain chicken and rice or cottage cheese. Also Pepcid Ac @ 0.5-1mg/kg every 12 hrs can be given to help with the nausea. He should recover from the adverse effects fully once the medication has been stopped completely. For future I would recommend treating his skin condition with a non-steroid such as Apoquel (excellent medication to use for Skin allergies in dogs).