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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Veterinary
Satisfied Customers: 26160
Experience:  University of California at Davis graduate veterinarian with 44 years of experience
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Type your Veterinary dog has reoccurring imt what's the

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Type your Veterinary dog has reoccurring imt what's the general prognosis nto question here
Submitted: 5 months ago via Dog-Health-Guide.
Category: Veterinary
Expert:  Dr. Michael Salkin replied 5 months ago.

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Expert:  Dr. Michael Salkin replied 5 months ago.

The prognosis for dogs who recrudesce (relapse without cure in between events) is guarded. When attempts to taper a patient off prednisone fail, treatment with another immunosuppressive drug - mycophenolate (alone) - is used for the long-term.

Melena (bleeding originating in the small intestine) and/or high blood urea nitrogen (BUN) concentration on the serum biochemistry profile have been associated with a worse prognosis in some reports.

To answer you directly, many pets can be completely tapered from immunosuppressive medications although recrudescence remains possible; there's a 9% documented recurrence rate in dogs. Many animals are euthanized due to adverse effects of glucocorticosteroids. Strategies to decreased steroid adverse effects include avoidance of obesity, use of an additional immunosuppressive agent (vincristine, mycophenolate, e.g.) to lower steroid dosage, and routine monitoring for infections of the skin and urinary tract. Stressful circumstances should be avoided if possible to avoid triggering relapse during remission and to reduce the risk of minimal but catastrophic self-trauma during severe thrombocytopenia. Routine monitoring should be scheduled to detect recrudescence of disease and side effects of immunosuppressive medications. Weight must be carefully monitored and obesity avoided.

Please respond with further questions or concerns if you wish.