when i began giving flea medicine yesterday, Linda was here, and she asked me if i should hold off on Tinker because there might be an interaction between the insulin and the frontline. i didn't see why there should have been. only that the insulin is given in the back around the area where the frontline is given. the insulin injection site is rotated though. the frontline was given after the insulin yesterday morning, separated by about 2 hours. the frontline is a lot of gooey liquid that drips all over and although it seems like 0.5 mls is a little bit, everyone had huge wet smears all over them. figure Tinker got his frontline at about 10 AM. he later got the 1 1/2 mls insulin at 7:30 PM. but his behavior, as you say, was as if the insulin wasn't enough for him. he was behaving as he had been, before we ever started the insulin.
i haven't given any de-wormer. that might happen in about 2 weeks.
in any event, Tinker seems a lot better this evening. i had given his 1 1/2 mls this morning at 7:30 AM. he had started to improve somewhat and i had this busy day ahead of me. so i left the house with Linda and when i returned, at about 3 PM, Tinker seems to be much much better.
so what do you think? the frontline increases insulin resistance or denatures the insulin that's being injected? they both must be competing for the same sites since they both get absorbed in the back under the skin.