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Hello, this is Dr. David. I am reviewing your question now and will be with you momentarily.
you should ask your doctor to get a skin or wound culture of the area of your nephrostomy tube to see if there is an actual infection there.
most likely taking levofloxacin antibiotic will not damage your kidneys
it can be a hard area for you to see and examine your nephrostomy tube area.
you don't want an infection to get worse there and potentailly threaten your kidneys as well.
you should take the full course of the antibiotic and follow up with your doctor.
and take a probiotic as well and eat yogurt to help add good bacteria into your GI system to prevent diarrhea from taking antibiotics
let me know if you have questions.