Uro-Vaxom has certainly been around for some times AND some studies have shown its effiacy in prevenyting UTI's caused by E.Coli ONLY, however the studies which showed its benefits were done in a very small subset of patients. The one done in 2011 was in 127 patients, the one in 2009 was done in 80 or so patients. In order for a medical product to prove its efficacy, double blind randomized clinicla trials have to be done in a large group of patients. This is because when we have a large group, that will be more represntative of the general population and will statistically be more significant in proving its efficacy.
Now that doesn't mean this product is not useful, it certainly is however it is still being studied. As i said earlier, there are various vaccines which are under development and Uro-vaxom or rather a variant of this vaccine is currently under trials. There is a high probablity that the trials will show that this vaccine certainly works. But this vaccine will confer immunity ONLY against the various strains of E.Coli, NOT against any other bacteria which can cause UTI such a klebsiella, pseudomonas or enterococcus.
The science behind it is certainly valid, and it does show promise however in order for it to be accepted into general medical treatment guidelines, it has to first show its efficacy in preventing E.coli infections. The evidence so far, while promising, is not enough to promote its general use. The current clinical trials are also looking into the potential side effects which can occur with various vaccines.
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