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Have you looked at your tenancy agreement to see if it contains a break clause entitling your to terminate the agreement earlier than the fixed term?
Does the tenancy agreement allow you to assigning (ie. selling the remaining term to a replacement tenant) or subletting the premises?
I'm afraid that unless there is a clause in the lease entitling you to terminate in the event of your ill health then you are not permitted to terminate on this basis. It would up to the landlord to decide whether they wish to surrender the lease in view of the letter but they are under no obligation to do so.
Send the letter to the landlord stating that you wish to seek their instructions on whether they would be willing to surrender the lease. They may accept, they may accept subject to you paying them some money or they may refuse and hold you to the contract.
If you simply stopped paying the rent then they will forfeit the lease and sue you for the remaining rent. They would probably obtain judgement on an amount equal to the rent that they would have earned up to the point at which the pub could be relet to another tenant because they are under a duty to mitigate their loss.
As an interim measure you may seek to find a bar manager who can manage the day to day running of the property in the hope that it produces enough income to cover, or partially cover, the rent until you can find a replacement tenant.
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