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Papaverine Related Questions

Papaverine is a drug that belongs to a group of medications known as vasodilators. This medication often helps increase the flow of blood by expanding the blood vessels. It is commonly used in order to treat individuals with erectile dysfunction. The medicine increases the blood flow in the penis thereby helping it to cause an erection. When an individual is using this medication or has recently been prescribed this medication, questions may arise regarding the treatment, possible side effects, common complications and the dosage. Read below where some of the commonly asked questions about Papaverine have been answered by Experts.

What is the shelf life of the medication Papaverine 9 milligrams with Phentolamine 1 milligram and Prostaglandin 10 microgram?

The shelf life of the medication Papaverine 9 milligrams is typically 90 days. It may be safe to still take the medication for about three days after it has expired. However, it may not be safe to take this medication 10 days past the expiration date.

Is Papaverine 9 milligrams available over the counter?

Papaverine 9 milligrams is a prescription medication. Hence, it's usually not available over the counter and one may need a doctor’s prescription to buy it.

Is it normal for an individual to have an erection almost 4 ½ hours after injecting Papaverine?

It is usually not normal for an individual to have an erection for almost 4 ½ hours after injecting Papaverine. This may be an indication of the side effects of this medication. The condition is known as priapism. The individual may need to be seen in the Emergency Room as soon as possible so that a doctor can examine the condition and give the appropriate medication. A delay in going to the Emergency Room may often lead to further complications.

What are the most commonly used solutions in injection therapy?

In some cases, mono therapy with a single drug solution may often be used in injections. However, the most common solutions used are Papaverine, Cavarject and Edex. In some situations, two of the solutions may be mixed together. Such a solution is often referred to as a bi mix solution. In some other cases, all three solutions may be mixed together to get a tri mix solution.

What is Trimix?

Trimix is an injectable medication that is often used in order to treat erectile dysfunction. Trimix is made up of three drugs -- Alprostadil, Papaverine and Phentolamine. The medication is normally made in a pharmacy in a sterile environment and then frozen. One milliliter of injection usually contains 10 micrograms of Alprostadil, 30 milligrams of Papaverine and 1 milligram of Phentolamine.

What are the general side effects of Trimix?

Each of the three different medications used in a Trimix may have their specific side effects. However, the general side effects of all of these medications are given below:
• Priapism or prolonged erection
• Fibrosis of the penis
• Penile pain
• Bruising at the site of injection
• Low blood pressure
• Increased heart rate or reflex tachycardia
• Nasal congestion
• Stomach upset

What would happen if an erection caused by an overdose of Papaverine is not reversed on time?

An erection caused due to an overdose of Papaverine is often referred to as Ischemic Priapism. If this is not reversed within 24 hours, the chances of preserving potency may only be about 20%. These chances are further reduced if the erection has lasted for more than 24 hours. The damage to the penis is often caused due to the formation of scar tissue because of the erection. The chances of this tissue responding to any kind of medications may be very rare because the tissue is just a scar and does not have any kind of erection properties.

How is a Priapism caused due to an overdose of Papaverine treated?

One may have to be seen in the Emergency Room in order to get treated for priapism that has been caused due to the overdose of Papaverine. A doctor may insert a needle in the penis in order to remove the blood and inject a reversal agent. This procedure usually needs to be conducted within 4-8 hours of the erection for it to be successful.

Even though many individuals take Papaverine in order to treat erectile dysfunction, there are certain side effects that these individuals need to be aware of. It is important to have knowledge of the correct dosage in order to avoid most of these side effects. The more individuals read about this drug before using it, the more questions the individual may have about who can take this medication, the right time to take it and its effectiveness. If you have these or any other questions about Papaverine, you can ask an Expert and get as much information as needed.

Ask a Doctor

Dr. Thomas, MD
Dr. Thomas, MD, Board Certified Physician
Category: General
Satisfied Customers: 47404
Experience:  Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
24257177
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Dr. Thomas, MD
Board Certified Physician
Satisfied Customers: 46349
Internal Medicine--practice all of internal medicine, all ages, family, also Integrative, CAM, etc
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Medical Degree, Former Assistant Professor at School of Medicine at Yale University

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