Thank you for your question
Unfortunately if you are a 2% (or higher) shareholderin a S Corp, a partner in a formal business partnership, or otherwise self employed, then you can't contribute pre-tax contributions to your HSA because in this case you are essentially your own employer. For technical details, you can check out IRS Notice 2005-8.
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Lane, 100% owner of a C Corp. Does that change your answer? I'd like to deduct from the C Corp, not the individual return.