Yes, you can continue to deduct the mortgage interest on your home in Nevada. In general, the IRS allows you to deduct mortgage interest for your main home and a secondary home. This is still going to be considered your main home even though you may not currently be residing there.
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It will not matter whether or not you change your address with the IRS. You will still be allowed this deduction. It would probably be best to change your address to be certain that you get any necessary correspondence from the IRS on a timely basis, and it will not affect your mortgage interest deduction whatsoever. Mortgage interest is deductible not only on your main home, but also on a second home (such as a vacation condo), so many people have one address with the IRS and yet take mortgage interest deductions for two residences.
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