I'm happy to help you with this. Do you have any pictures of the area? Is this in a basement?
Some holes are OK in the skinny part of the beam (called the web), but it depends on a lot of factors:
I see now that you requested a live phone call. I'd be happy to speak with you, I'll send an additional service offer shortly.
If you are unable to speak via phone, I'm happy to continue chatting with you. Can you give me an idea of the factors I mentioned above?